Phytotherapeutics for parasite control in global fish aquaculture: a review of anti-monogenean agents and their mechanisms

Open Access

Review

Issue		Aquat. Living Resour. Volume 39, 2026


Article Number		3
Number of page(s)		32
DOI		https://doi.org/10.1051/alr/2025021
Published online		03 February 2026

Acharya A, Saha H, Pal P. 2025. In vitro and in vivo antiparasitic efficacy of aqueous mahua oil cake extract against Argulus foliaceus infestation in Cyprinus carpio (Linneaus, 1758). Acta Parasitol 70: 1–9. [Google Scholar]
Ahmad S, Humak F, Ahmad M, Altaf H, Qamar W, Hussain A, Ashraf U, Abbas RZ, Siddique A, Ashraf T, Mughal MAS, 2023. Phytochemicals as alternative anthelmintics against poultry parasites: a review. Agrobiol Rec 12: 34–45. [Google Scholar]
Akram M, Mahmood K. 2024. Awareness and current knowledge of medicinal plants. RPSPPR 3: 1–5. [Google Scholar]
Alijanpour Z, Rahmati-Holasoo H, Mousavi HE, Saeed Mirzargar S, Sharifzadeh A, Nasiri A. 2022. In vitro study of effects of alcoholic extract of Chelidonium majus L. on Ichthyophthirius multifiliis theronts. J Fish 75(3): 405–417. [Google Scholar]
Almeida-Couto JMF, Ressutte JB, Cardozo-Filho L, Cabral VF. 2022. Current extraction methods and potential use of essential oils for quality and safety assurance of foods. An Acad Bras Cienc 94(2): 10–20. [Google Scholar]
Alves CMG, Nogueira JN, Luz JGR, Chaves FCM, Tavares-Dias M. 2021. Essential oil of Piper callosum, Piper hispidum and Piper marginatum (Piperaceae) possesses in vitro efficacy against monogeneans of Colossoma macropomum (tambaqui). Aquac Res 52: 6107–6116. [Google Scholar]
Alves CMG, Jesus Baia RR, Farias VA, Farias MA, Souza FLS, Videira MN, Chaves FCM, Yoshioka ETO, Tavares-Dias M. 2024a. Essential oil of Piper hispidum (Piperaceae) has efficacy against monogeneans, and effects on hematology and gill histology of Colossoma macropomum. Rev Brasil Parasitol Vet 33: 1–8. [Google Scholar]
Alves CMG, Baia RRJ, Pacheco AM, Carvalho AA, Farias VA, Videira MN, Chagas FCM, Yoshioka ETO, Tavares-Dias M. 2024b. Essential oil of Piper marginatum (Piperaceae) against monogeneans, and its hematological and histopathological effects on Colossoma macropomum. Acta Parasitol 69: 1212–1218. [Google Scholar]
Alves CMG, Baia RRJ, Santos PVN, Pacheco AM, Videira MN, Chaves FCM, Yoshioka ETO, Tavares-Dias, M. 2025. Efficacy of therapeutic baths with Piper callosum essential oil against monogeneans of Colossoma macropomum: hematological and histopathological assessments. Braz J Vet Parasit 34: e002625. [Google Scholar]
Andrade JIA, Jerônimo GT, Brasil EM, Nunez CV, Gonçalves ELT, Ruiz ML, Martins ML. 2016. Efficacy of seed extract of Bixa orellana against monogenean gill parasites and physiological aspects of Colossoma macropomum after bath treatment. Aquaculture 462: 40–46. [Google Scholar]
Anjos ACP, Isaac A. 2020. The efficacy and dosage of Mentha piperita essential oil in the control of Monogenean parasites in Oreochromis niloticus. J Paras Dis 44: 597–606. [Google Scholar]
Assane IM, Prada-Mejia KD, Gallani SU, Weiser NF, Valladão GMR, Pilarski F. 2022. Enterogyrus spp. (Monogenea: Ancyrocephalinae) and Aeromonas jandaei co-infection associated with high mortality following transport stress in cultured Nile tilapia. Transbound Emerg Dis 69: 276–287. [Google Scholar]
Attia MM, Alzahrani AM, Hanna MI, Salem HM, Abourehab MAS, El-Saadony MT, Thabit H. 2022. The biological activity of Illicium verum (Star Anise) on Lernaea cyprinacea-infested Carassius auratus (goldfish): In vivo study. Life 12: 2–17. [Google Scholar]
Ávila-Castillo R, Río-Rodríguez RD, Mendoza-Carranza M, Cu-Escamilla A, Gómez-Solano M, Paredes-Trujillo A. 2024. Cichlidogyrosis in tropical aquaculture: pathological effects and infection dynamics in Nile tilapia Oreochromis niloticus, a case study in Campeche, Mexico. J Appl Aquacult 1–23. [Google Scholar]
Baia RRJ, Alves CMG, Oliveira MSB, Salomão CB, Carvalho AA, Videira MN, Yoshioka ETO, Tavares-Dias, M. 2024. Albendazole is effective in controlling monogeneans in Colossoma macropomum (Serrasalmidae): therapeutic baths and their physiological and histopathological effects. Braz J Vet Parasit 33: e004924. [Google Scholar]
Bandeira DM, Corrêa JM, Laskoski LV, Rosset J, Conceição LHSM, Gomes SD, Pinto FGS. 2024. Phytochemical screening of Podocarpus lambertii Klotzch ex Endl. leaf extracts and potential antimicrobial, antioxidant and antibiofilm activity. An Acad Bras Cienc 96(3): 1–16. [Google Scholar]
Bandeira-Jr G, Pês TS, Saccol EMH, Sutili FJ, Rossi WR, Murari AL, Heinzmann BM, Pavanato MA, Vargas AC, Silva LL, Baldisserotto B. 2017. Potential uses of Ocimum gratissimum and Hesperozygis ringens essential oils in aquaculture. Ind Crops Prod 97: 484–491. [Google Scholar]
Barriga IB, Gonzales APPF, Brasiliense ARP, Castro KNC, Tavares-Dias M. 2020. Essential oil of Lippia grata (Verbenaceae) is effective in the control of monogenean infections in Colossoma macropomum gills, a large Serrasalmidae fish from Amazon. Aquac Res 51: 3804–3812. [Google Scholar]
Boijink CL, Miranda WSC, Chagas EC, Dairiki JK, Inoue, LAKA. 2015. Anthelmintic activity of eugenol in tambaquis with monogenean gill infection. Aquaculture 438: 138–140. [Google Scholar]
Boopathi S, Kesavan D, Sudhakaran G, Priya PS, Haridevamuthu B, Dhanaraj M, Seetharaman S, Almutairi BO, Arokiyaraj S, Guru A, Arockiaraj J. 2024. Exploring the efficacy of pellitorine as an antiparasitic agent against Argulus: impacts on antioxidant levels and immune responses in goldfish (Carassius auratus). Acta Parasitol 69: 734–746. [Google Scholar]
Brabec J, Salomaki ED, Kolísko M, Scholz T, Kuchta R. 2023. The evolution of endoparasitism and complex life cycles in parasitic platyhelminths. Curr Biol 33: 4269–4275. [Google Scholar]
Brasil EM, Figueiredo AB, Cardoso L, Santos MQC, Bertaglia EA, Furtado WE, Viana JS, Carmo IB, Chaves FCM, Mouriño JLP, Martins ML. 2019. In vitro and in vivo antiparasitic action of essential oils of Lippia spp. in koi carp (Cyprinus carpio) fed supplemented diets. Brazil J Vet Pathol 12: 88–100. [Google Scholar]
Caña-Bozada VH, García-Gasca A, Martínez-Brown JM, Morales-Serna FN. 2024. Evaluation of bromocriptine and plumbagin against the monogenean Rhabdosynochus viridisi: computational drug repositioning and in vitro approaches. Exp Parasitol 261: 1–9. [Google Scholar]
Chika IB, Onyekachi OJ, Chioma IF, Emmanuel A, Rose ON, Bernard MO. 2020. Antiparasiticidal potential of Aqueous leaves extract of Moringa oleifera against Ichthyophthirius multifiliis infestation on Clarias gariepinus. J Anim Health Prod 8: 113–121. [Google Scholar]
Chong CM, Ganaseh-Murthy AVS, Choy CY, Lai KS. 2020. Phytotherapy in aquaculture: integration of endogenous application with science. J Environ Biol 41: 1204–1214. [Google Scholar]
Cornejo-Rigaud A, Estela N, Paredes M, Delgado PM, Mertins O, Tavares-Dias M, Fernández-Méndez C, Gonzales AF. 2025. Anthelmintic efficacy of ethanolic extracts from two Jatropha species against monogenean gill parasites and hematological and histopathological effects on Piaractus brachypomus. Vet Parasitol 340: 110601. [Google Scholar]
Corral ACT, Queiroz MN, Andrade-Porto SM, Morey GAM, Chaves FCM, Fernandes VLA, Ono EA, Affonso EG. 2018. Control of Hysterothylacium sp. (Nematoda: Anisakidae) in juvenile pirarucu (Arapaima gigas) by the oral application of essential oil of Piper aduncum. Aquaculture 494: 37–44. [Google Scholar]
Costa CMS, Cruz MG, Lima TBC, Ferreira LC, Ventura AS, Brandão FR, Chagas EC, Chaves FCM, Martins ML, Jerônimo GT. 2020. Efficacy of the essential oils of Mentha piperita, Lippia alba and Zingiber officinale to control the acanthocephalan Neoechinorhynchus buttnerae in Colossoma macropomum. Aquac Rep 18: 1–9. [Google Scholar]
Costa JC, Valladão GMR, Pala G, Gallani SU, Kotzent S, Crotti AEM, Fracarolli L, Silva JJM, Pilarski F. 2017. Copaifera duckei oleoresin as a novel alternative for treatment of monogenean infections in pacu Piaractus mesopotamicus. Aquaculture 471: 72–79. [Google Scholar]
Cunha JA, Sutili FJ, Oliveira AM, Gressler LT, Scheeren CDA, Silva LDL, Vaucher RDA, Baldisserotto B, Heinzmann BM. 2017. The essential oil of Hyptis mutabilis in Ichthyophthirius multifiliis infection and its effect on hematological, biochemical, and immunological parameters in silver catfish, Rhamdia quelen. J Parasitol 103: 778–785. [Google Scholar]
Dadras F, Velisek J, Zuskova E. 2023. An update about beneficial effects of medicinal plants in aquaculture: a review. Vet Med 68(12): 449–463. [Google Scholar]
Doan HV, Soltani E, Ingelbrecht J, Soltani M. 2020. Medicinal herbs and plants: potential treatment of monogenean infections in fish. Rev Fish Sci Aquacul 28: 260–282. [Google Scholar]
Elgendy MY, Ali SE, Dayem AA, Khalil RH, Moustafa MM, Abdelsalam M. 2024. Alternative therapies recently applied in controlling farmed fish diseases: mechanisms, challenges, and prospects. Aquacult Int 32: 9017–9078. [Google Scholar]
FAO. The State of World Fisheries and Aquaculture 2024–Blue Transformation in Action, 2024. Rome. https://doi.org/10.4060/cd0683en [Google Scholar]
Faria JMS, Silva IV. 2022. Anti-nematodal essential oils with activity against anisakis. Med Sci Forum 7: 1–6. [Google Scholar]
Ferreira LC, Cruz MG, Lima TBC, Serra BNV, Chaves FCM, Chagas EC, Ventura AS, Jerônimo GT. 2019. Antiparasitic activity of Mentha piperita (Lamiaceae) essential oil against Piscinoodinium pillulare and its physiological effects on Colossoma macropomum (Cuvier, 1818). Aquaculture 512: 734343. [Google Scholar]
Fu YW, Zhang QZ, Xu DH, Xia H, Cai XX, Wang B, Liang J. 2014. Parasiticidal effects of Morus alba root bark extracts against Ichthyophthirius multifiliis infecting grass carp. Dis Aquat Org 108: 129–136. [Google Scholar]
Fu YW, Wang B, Zhang QZ, Xu DH, Liu YM, Hou TL, Guo SQ. 2019. Efficacy and antiparasitic mechanism of 10-gingerol isolated from ginger Zingiber officinale against Ichthyophthirius multifiliis in grass carp. Vet Parasitol 265: 74–84. [Google Scholar]
Fu YW, Guo SQ, Luo JJ, Sang CG, Lin DJ, Liu YM, Zhang QZ. 2021. Effectiveness assessment of plant mixtures against Ichthyophthirius multifiliis in grass carp Ctenopharyngodon idella. Aquaculture 530: 735742. [Google Scholar]
Fu YW, Liu WD, Chen HZ, Lin DJ, Hou TL, Guo SQ, Zhang QZ. 2022. Antiparasitical efficacy of sophoraflavanone G isolated from Sophora flavescens against parasitic protozoa Ichthyophthirius multifiliis. Vet Parasitol 306: 109731. [Google Scholar]
Girotto LM, Herrig SPR, Nunes MGIF, Sakai OA, Barros BCB. 2025. Extraction of phenolic compounds from Pfaffia glomerata leaves and evaluation of composition, antioxidant and antibacterial properties. An Acad Bras Cienc 97(2): 1–13. [Google Scholar]
Gobbin TP, Vanhove MPM, Veenstra R, Maan ME, Seehausen O. 2023. Variation in parasite infection between replicates of speciation in Lake Victoria cichlid fish. Evolution 77: 1682–1690. [Google Scholar]
Gómez-Rincón C, Langa E, Murillo P, Valero MS, Berzosa C, López V. 2014. Activity of tea tree (Melaleuca alternifolia) essential oil against L3 larvae of Anisakis simplex. Biomed Res Int 3: 1–6. [Google Scholar]
Gonzales AF, Mamani V, Pereyra M, Aguilar E, Mathews PD, Tavares-Dias M, Fernández-Méndez C. 2022. In vitro efficacy and tolerance of the essential oils of three species of the Lamiaceae family against monogeneans from the gills of Piaractus brachypomus from the Peruvian Amazon. Aquacult Int 30: 2245–2261. [Google Scholar]
Gonzales APPF, Santos GG, Tavares-Dias M. 2019. Anthelminthic potential of the Ficus insipida latex on monogeneans of Colossoma macropomum (Serrasalmidae), a medicinal plant from the Amazon. Acta Parasitol 64: 927–931. [Google Scholar]
Gonzales APPF, Yoshioka ETO, Mathews PD, Mertins O, Chaves FCM, Videira MN, Tavares-Dias M. 2020. Anthelminthic efficacy of Cymbopogon citratus essential oil (Poaceae) against monogenean parasites of Colossoma macropomum (Serrasalmidae), and blood and histopathological effects. Aquaculture 528: 735500. [Google Scholar]
Grano-Maldonado MI, Rodríguez-Santiago MA, García-Vargas F, Nieves-Soto M, Soares F. 2018. An emerging infection caused by Gyrodactylus cichlidarum Paperna, 1968 (Monogenea: Gyrodactylidae) associated with massive mortality on farmed tilapia Oreochromis niloticus (L.) on the Mexican pacific coast. Lat Am J Aquat Res 46: 961–968. [Google Scholar]
Guo W, Wei D, Zhao Z, Hu F, Wang D, Tang W, Wang Y, Deng H, Li J, Zhang D, Zhong Z, Zhou Y. 2025. Pharmacokinetics of honokiol in Trachinotus ovatus following administration of honokiol monomer and Magnolia officinalis extracts. Aquaculture 604: 742438. [Google Scholar]
Han W, Yang K, Tan X, Gao L, Qu S, Zhang G, Fan W, Liu M, Wang E, Li P, Ling F, Wang G, Liu T. 2024. Curcumin is an efficacious therapeutic agent against Chilodonella uncinata via interaction with tubulin alpha chain as protein target. Fish Shellfish Immunol 15: 109961. [Google Scholar]
Hanna MI, El Sayed AT, El-Megeed OHA, Ibrahim MA, Korany RMS, Attia MM. 2025. Assessment of a new protocol strategy to control the ectoparasitic infestation in Nile tilapia (Oreochromis niloticus) using efficient natural products. BMC Vet Res 21(15): 1–14. [Google Scholar]
Haridevamuthu B, Raj D, Arshad A, Arockiaraj J. 2024. Comprehensive review of Argulus infestations in aquaculture: Biological impacts and advanced management strategies. Fish Shellfish Immunol 153: 109851. [Google Scholar]
Hassan JRT, Yakhchali M, Nekoueifard A. 2024. Study on effects of plants extracts of Thymus vulgaris and Lavandula angustifolia on Ichthyophthirius multifiliis in rainbow trout (Oncorhynchus mykiss). Iranian J Anim Sci 55: 461–475. [Google Scholar]
Hoai TD. 2020. Reproductive strategies of parasitic flatworms (Platyhelminthes, Monogenea): the impact on parasite management in aquaculture. Aquacult Int 28: 421–447. [Google Scholar]
Hu J, Yang H, Tu X, Gu Z. 2023. Epicatechin gallate: A promising agent isolated from Sargentodoxa cuneata for the treatment of ichthyophthiriasis in goldfish (Carassius auratus). Aquaculture 574: 739724. [Google Scholar]
Hu Y, Ji J, Ling F, Chen Y, Lu L, Zhang Q, Wang G. 2014. Screening medicinal plants for use against Dactylogyrus intermedius (Monogenea) infection in goldfish. J Aquat Anim Health 26: 127–136. [Google Scholar]
Hu Y, Liu L, Liu GL, Tu X, Wang GX, Ling F. 2017. Synthesis and anthelmintic activity of arctigenin derivatives against Dactylogyrus intermedius in goldfish. Bioorg Med Chem Lett 27: 3310–3316. [Google Scholar]
Huang AG, Yi YL, Ling F, Lu L, Zhang QZ, Wang GX. 2013. Screening of plant extracts for anthelmintic activity against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus). Parasitol Res 112: 4065–4072. [Google Scholar]
Huang K, Hu G, Wang R, Zeng Q, Li W, Zou H, Wu S, Wang G, Li M. 2022. In vitro Assessment of berberine against Ichthyophthirius multifiliis in goldfish. Pathogens 112: 4065–4072. [Google Scholar]
Hyun-Kim J, Fridman S, Borochov-Neori H, Sinai T, Zilberg D. 2019. Evaluating the use of garlic (Allium sativum) for the remedy of Cryptocaryon irritans in guppies (Poecilia reticulata). Aquac Res 50: 431–438. [Google Scholar]
Ingelbrechta J, Millera TL, Lymberya AJ, Maitac M, Torikaic S, Partridgea G. 2020. Anthelmintic herbal extracts as potential prophylactics or treatments for monogenean infections in cultured yellowtail kingfish (Seriola lalandi). Aquaculture 520: 734776 [Google Scholar]
Ikele CB, Uju UV, Ikele CF. 2024. Anti-parasite activity of different plant leaf extracts against infective stage theront of Ichthyophthirius multifiliis. J Anim Health Prod 12: 196–204. [Google Scholar]
Jatobá A, Stockhausen L, Silva LR, Andrade JIA. 2023. Therapeutic bath of mint hydrolate in the control of monogenea for four tilapia species. Bol Inst Pesca 49: 1–7. [Google Scholar]
Jetithor SG, Nalle AD, Ghate S. 2025. Assessment of the anthelminthic properties of Vernonia amygdalina, a medicinal plant extract, against fish monogenean parasites. IJRAR 12(1): 57–62. [Google Scholar]
Jeyavani J, Sibiya A, Sivakamavalli J, Divya M, Preetham E, Vaseeharan B, Faggio C. 2022. Phytotherapy and combined nanoformulations as a promising disease management in aquaculture: a review. Aquacult Int 30: 1071–1086. [Google Scholar]
Ji J, Gong X, Liu G, Yin S, Ling F, Wang G. 2025. Antiparasitic effect of (+)-catechin derived from Pseudolarix amabilis against Dactylogyrus intermedius in goldfish. Vet Parasitol 334: 110399. [Google Scholar]
Khoris AA, Bileh SS. 2024. Effect of Artemisia extract on Argulus coregoni and Lernaea cyprinacea infestation in carp fish. J Adv Vet Res 14(6): 969–974. [Google Scholar]
Kilibarda S, Jović MD, Milinčić DD, Vuković S, Trifković J, Pešić MB, Kostić A. 2025. Phytochemical profile and biological activities of Rtanj's Hypericum perforatum infusion tea and methanolic extracts: insights from LC-MS/MS and HPTLC–bioautography. Plants 14: 1377. [Google Scholar]
Kim J, Yoon S, Mansoor S, Jung CY, Kim CS, Boo KH. 2025. Parasiticidal activity of citral against Enteromyxum leei (Myxozoa: Myxosporea) in olive flounder (Paralichthys olivaceus). Acta Parasitol 70: 74. [Google Scholar]
Kuebutornye FKA, Abarike ED. 2020. The contribution of medicinal plants to tilapia aquaculture: a review. Aquacult Int 28: 965–983. [Google Scholar]
Kumari P, Kumar S, Ramesh M, Shameena S, Deo AD, Rajendran KV, Raman RP. 2019. Antiparasitic effect of aqueous and organic solvent extracts of Azadirachta indica leaf against Argulus japonicus in Carassius auratus. Aquaculture 511: 634175. [Google Scholar]
Kumari P, Kumar S, Raman RP, Brahmchari RK. 2024. Nanotechnology: an avenue for combating fish parasites in aquaculture system. Vet Parasitol 333: 110334. [Google Scholar]
Kumari P, Kumar S, Brahmchari RK, Singh AB, Rajendran KV, Shukla SP, Sharma R, Raman RP. 2025. Anti-parasitic efficacy of green-synthesized silver nanoparticles on Argulus siamensis: an ectoparasite of fish and their effect on the expression of ion channel genes. Aquacult Int 33: 83. [Google Scholar]
Larcombe E, Alexander ME, Snellgrove D, Henriquez FL, Sloman KA. 2025. Current disease treatments for the ornamental pet fish trade and their associated problems. Rev Aquac 17: e12948. [Google Scholar]
Leis E, Bailey J, Katona R, Standish I, Dziki S, McCann R, Perkins J, Eckert N, Baumgartner W. 2023. A mortality event involving Endangered Pallid Sturgeon (Scaphirhynchus albus) associated with Gyrodactylus conei n. sp. (Monogenea: Gyrodactylidae) effectively treated with parasite-S (Formalin). Parasitologia 3: 205–214. [Google Scholar]
Les F, Galiffa V, Cásedas G, Moliner C, Maggi F, López V, Gómez-Rincón C. 2024. Essential oils of two subspecies of Satureja montana L. against gastrointestinal parasite Anisakis simplex and acetylcholinesterase inhibition. Molecules 29: 4640. [Google Scholar]
Leśniak P, Puk K, Guz L. 2021. Parasiticidal effects of Eclipta alba and Arctium lappa extracts against Ichthyophthirius multifiliis. Pol J Vet Sci 2494: 547–552. [Google Scholar]
Levy G, Zilberg D, Paladini G, Fridman S. 2015. Efficacy of ginger-based treatments against infection with Gyrodactylus turnbulli in the guppy (Poecilia reticulata (Peters). Vet Parasitol 209: 235–241. [Google Scholar]
Li Y, Zhou W, Cui Y, Zhou P, Shan Y, Jin N, Ye S. 2025. A safe antiparasitic extract from Psoralea corylifolia for Tetrahymeniasis control. Vet Parasitol 333: 110341. [Google Scholar]
Lian K, Zhang M, Zhou L, Song Y, Guan X. 2020. Screening of Chinese medicinal herbs for anthelmintic efficacy against Gyrodactylus kobayashii (Monogenea) in goldfish (Carassius auratus). Kafkas Univ Vet Fak Derg 26(3): 357–363. [Google Scholar]
Ling F, Jiang C, Liu G, Li M, Wang G. 2015. Anthelmintic efficacy of cinnamaldehyde and cinnamic acid from cortex cinnamon essential oil against Dactylogyrus intermedius. Parasitology 142: 1744–1750. [Google Scholar]
Liu GL, Li D, Song WW, Zhu LL, Han JW, Li YW, Wang CJ, Wang GX, Chen YH. 2022. A novel antiparasitic medicine from coumarins against Dactylogyrus intermedius infection in goldfish using 3D-QSAR model. Aquaculture 548: 1–8. [Google Scholar]
Liu GL, Zhang H, Zhu LL, Liu XD, Liu YJ, Chen YH, Liu L, Hu Y. 2023. Synthesis and anti-parasites efficacy of coumarin derivatives against Dactylogyrus intermedius. J Fish Dis 46: 967–976. [Google Scholar]
Liu HR, Liu YM, Hou TL, Li CT, Zhang QZ. 2021. Antiparasitic efficacy of crude plant extracts and compounds purified from plants against the fish monogenean Neobenedenia girellae. J Aquat Anim Health 33: 155–161. [Google Scholar]
Liu Y, Tan X, Zhang Y, Ling F, Liu T, Wang G. 2022. Isoimperatorin: A promising anti Gyrodactylus kobayashii natural compound from Angelica dahurica. Aquaculture 560: 738552. [Google Scholar]
López V, Cascella M, Benelli G, Maggi F, Gómez-Rincón C. 2018. Green drugs in the fight against Anisakis simplex-larvicidal activity and acetylcholinesterase inhibition of Origanum compactum essential oil. Parasitol Res 117: 861–867. [Google Scholar]
Luz JGR, Nogueira JN, Alves CMG, Videira MN, Canuto KM, Castro KNC, Tavares-Dias M. 2021. Essential oil of Alpinia zerumbet (Zingiberaceae) has anthelmintic efficacy against monogenean of Colossoma macropomum (Characiformes: Serrasalmidae). Aquac Res 52: 5340–5349. [Google Scholar]
Luz JGR, Lacerda DAP, Correa EFL, Araújo GF, Araújo RF, Chaves FCM, Tavares-Dias M. 2025. Zingiber officinale (ginger), Curcuma longa (turmeric) and Cymbopogon nardus (lemon grass) essential oils have anti-dactylogyrideans potential in Colossoma macropomum Cuvier 1816 (tambaqui). Aquac Fish Fish 5: e70146. [Google Scholar]
Mahdy OA, Abdel-Maogood SZ, Mohammed FF. 2017. Effect of Verbesina alternifolia and Mentha Piperita oil extracts on newly excysted metacercaria of Euclinostomum Heterostomum (Rudolphi, 1809) (Digenea: Clinostomatidae) from naturally infected kidneys of Tilapia zillii in Egypt. J Egypt Soc Parasitol 47(3): 515–523. [Google Scholar]
Mahdy OA, Abdel-Maogood SZ, Abdelrahman HA, Fathy FM, Salem MA. 2022. Assessment of Verbesina alternifolia and Mentha piperita oil extracts on Clinostomum phalacrocoracis metacercariae from Tilapia zillii. Beni-Suef Univ J Basic Appl Sci 11: 48. [Google Scholar]
Malheiros DF, Sarquis IR, Ferreira IM, Mathews PD, Mertins O, Tavares-Dias M. 2020a. Nanoemulsions with oleoresin of Copaifera reticulata (Leguminosae) improve anthelmintic efficacy in the control of monogenean parasites when compared to oleoresin without nanoformulation. J Fish Dis 43: 687–695. [Google Scholar]
Malheiros DF, Sarquis IR, Ferreira IM, Mathews PD, Mertins O, Tavares-Dias M. 2020b. Nanoemulsions with oleoresin of Copaifera reticulata (Leguminosae) improve anthelmintic efficacy in the control of monogenean parasites when compared to oleoresin without nanoformulation. J Fish Dis 43: 687–695. [Google Scholar]
Malheiros DF, Videira MN, Carvalho AA, Salomão CB, Ferreira IM, Canuto KM, Yoshioka ETO, Tavares-Dias M. 2023. Efficacy of Carapa guianensis oil (Meliaceae) against monogeneans infestations: a potential antiparasitic for Colossoma macropomum and its effects in hematology and histopathology of gills. Rev Brasil Parasitol Vet 32(3): e007123. [Google Scholar]
Maran BAV, Josmeh D, Tan JK, Yong YS, Shah MD. 2021. Efficacy of the aqueous extract of Azadirachta indica against the marine parasitic leech and its phytochemical profiling. Molecules 26: 1908. [Google Scholar]
Mathiessen H, Jaafar RM, Al-Jubury A, Jørgensen LG, Kania PW, Buchmann K. 2021. Comparative in vitro and in vivo effects of feed additives on rainbow trout response to Ichthyophthirius multifiliis. North Amer J Aquac 83: 67–77. [Google Scholar]
Meneses JO, Couto MVS, Sousa NC, Cunha FS, Abe HA, Ramos FM, Chagas EC, Chaves FCM, Martins ML, Maria AN, Carneiro PCF, Fujimoto RY. 2018. Efficacy of Ocimum gratissimum essential oil against the monogenean Cichlidogyrus tilapiae gill parasite of Nile tilapia. Arq Bras Med Vet Zootec 70: 497–504. [Google Scholar]
Meng Y, Yang H, Tu X, Gu Z. 2025. In vitro and in vivo assessment of Nelumbo nucifera, Glycines testa, and Agrimonia eupatoria extracts against different developmental stages of Ichthyophthirius multifiliis. Aquaculture 604: 742465. [Google Scholar]
Miri BY. 2025. Essential oils: chemical composition and diverse biological activities: a comprehensive review. Nat Prod Commun 20(1): 1–29. [Google Scholar]
Mizuno S, Urawa S, Miyamoto M, Hatakeyama M, Sasaki Y, Koide N, Tada S, Ueda H. 2018. Effects of dietary supplementation with oregano essential oil on prevention of the ectoparasitic protozoans Ichthyobodo salmonis and Trichodina truttae in juvenile chum salmon Oncorhynchus keta. J Fish Biol 93: 528–539. [Google Scholar]
Mladineo I, Trumbić Ž, Ormad-García A, Palenzuela O, Sitjà-Bobadilla A, Manuguerra S, Ruiz CE, Messina CM. 2021. In vitro testing of alternative synthetic and natural antiparasitic compounds against the monogenean Sparicotyle chrysophrii. Pathogens 10: 980. [Google Scholar]
Monir MS, Bagum N, Rahman N, Ashaf-Ud-Doulah M, Bhadra A, Borty SC. 2018. Parasitic diseases and estimation of loss due to infestation of parasites in Indian major carp culture ponds in Bangladesh. Inter J Fish Aqua Stud 2(5): 118–122. [Google Scholar]
Morales-Serna FN, Caña-Bozada VH, López-Moreno DG, Medina-Guerrero RM, Morales-Serna JA, Fajer-Ávila EJ. 2019. In vitro efficacy of two terpenes against ancyrocephalid monogeneans from Nile tilapia. J Parasit Dis 43: 739–742. [Google Scholar]
Mukaila R, Ukwuaba IC, Umaru II. 2023. Economic impact of disease on small-scale catfish farms in Nigeria. Aquaculture 575: 739773. [Google Scholar]
Munguti JM, Mboya JB, Iteba JO, Kirimi JG, Obiero KO, Kyule DN, Opiyo MA, Njonge FK. 2024. Status and prospects of the ornamental fish industry in Kenya. Aquac Fish Fish 4: e172. [Google Scholar]
Mungwari CP, King'ondu CK, Sigauke P, Obadele BA. 2025. Conventional and modern techniques for bioactive compounds recovery from plants: review. Sci African 27: e02509. [Google Scholar]
Nizio DA, Fujimoto RY, Maria AN, Carneiro PCF, França CCS, Sousa NC, Brito AF, Sampaio TS, Arrigoni-Blank MF, Blank AF. 2018. Essential oils of Varronia curassavica accessions have different activity against white spot disease in freshwater fish. Parasitol Res 117: 97–105. [Google Scholar]
Ng JJY, Yusoff NAH, Elias NA, Norhan NAS, Harun NA, Abdullah F, Ishak AN, Hassan M. 2024. Phytotherapy use for disease control in aquaculture: a review of the last 5 years. Aquacult Int 32: 2687–2712. [Google Scholar]
Oliveira-Lima J, Maciel-Honda PO, Silva JBA, Moron SE. 2025. Anthelmintic activity of garlic (Allium sativum) against the monogenean Dawestrema cycloancistrium and trichodinids, and its physiological effects on pirarucu (Arapaima gigas). Vet Parasitol 338: 110511. [Google Scholar]
Oliveira MIB, Brandão FR, Tavares-Dias M, Barbosa BCN, Rocha MJS, Matos LV, Souza DCM, Majolo C, Oliveira MR, Chaves FCM, Chagas EC. 2024. Essential oils of Ocimum gratissimum, Lippia grata and Lippia origanoides are effective in the control of the acanthocephalan Neoechinorhynchus buttnerae in Colossoma macropomum. Aquaculture 578: 740043. [Google Scholar]
Özil Ö. 2023. Antiparasitic activity of medicinal plants against protozoan fish parasite Ichthyophthirius multifiliis. Isr J Aquacult-Bamid 75(2): 1–7. [Google Scholar]
Parvin S, Reza A, Das S, Miah MMU, Karim S. 2023. Potential role and international trade of medicinal and aromatic plants in the world. EJFOOD 5: 89–99. [Google Scholar]
Patil PK, Geetha R, Mishra SS, Abraham TJ, Solanki HG, Sharma SRK, Pradhan PK, Manna SK, Avunje S, Abhinaya D, Felix KT, Vinay TN, Paniprasad K, Paria A, Raja SA, Saraswathy R, Sahoo SN, Rathod R, Rameshkumar P, Baitha R, Thomas S, Dev AK, Jayanthi M, Swain P, Sanil NK, Jena JK. 2025. Unveiling the economic burden of diseases in aquatic animal food production in India. Front Sustain Food Syst 9: 1480094. [Google Scholar]
Pereira CD, Shimokawa C, Sugiyama H, Shiroyama M, Miura T. 2025. Effects of wood creosote on anisakiasis: A Japanese traditional medicine as a potential tool against Anisakis larva infection. Parasitol Int 108: 103077. [Google Scholar]
Pereira EC, Oliveira EC, Sousa EMO, Silva HNP, Corrêa LL, Mourão RHV, Tavares-Dias M, Silva LVF. 2020. Lethal concentration of Cymbopogon citratus (Poaceae) essential oil for Dolops discoidalis and Argulus sp. (Crustacea: Argulidae). J Fish Dis 43: 1497–1504. [Google Scholar]
Puk K, Guz L. 2021. Parasiticidal effects of Tanacetum vulgare extract against Ichthyophthirius multifiliis. Polish J Vet Sci 24: 159–161. [Google Scholar]
Queiroz MN, Torres ZES, Pohlit AM, Ono EA, Affonso EG. 2022. Therapeutic potential of Piper aduncum leaf extract in the control of monogeneans in tambaqui (Colossoma macropomum). Aquaculture 552: 738024. [Google Scholar]
Radwan M, Darweesh KF, Ghanem SF, Abdelhadi Y, Kareem ZH, Christianus A, Karim M, Waheed RM, El-Sharkawy MA. 2023. Regulatory roles of Pawpaw (Carica papaya) seed extract on growth performance, sexual maturity, and health status with resistance against bacteria and parasites in Nile tilapia (Oreochromis niloticus). Aquacult Int 31: 2475–2493. [Google Scholar]
Radwan M, Abbas MMM, Fares M, Moussa MA, Mohammadein A, Al Malki JS, Mekky AE, Yassir S, Aboezz Z, Elraey SMA. 2024. Evaluation of Azadirachta indica leaf extracts efficacy against gill flukes' parasites with a focus on oxidative stress, pathological changes, and immune gene response in infected Nile tilapia. Aquacult Int 32: 10029–10051. [Google Scholar]
Rahman AN, Farag MFM, Khalil AA, Younis EM, Abdelwarith AA, Masoud SR, Bazeed SM, Elgamal A, Ras R, Davies SJ, Ibrahim RE, Abd El-Ghany AM. 2024. The anti-parasitic effect of Melaleuca alternifolia oil against gills monogeneans (Dactylogyrus spp) infestation of Clarias gariepinus: hematology, immune response, and histopathological/immuno histochemical investigation of gills. Aquaculture 584: 740639. [Google Scholar]
Rahmati-Holasoo H, Asadi A, Nassiri A, Mousavi HE, Nabian S. 2024. In vitro study of effects of alcoholic extract of pomegranate peel on Ichthyophthirius multifiliis theronts. J Med Plants By-Products 13: 644–652. [Google Scholar]
Rahmati-Holasoo H, Nassiri. 2025. Effects of mixed extract of thyme, mint and ginger on Ichthyophthirius multifiliis theronts: in vitro study. Int J Aquat Res Environ Stud 5(1): 1–16. [Google Scholar]
Reda R, Khalil AA, Elhady M, Tayel SI, Ramadan EA. 2024. Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) extracts against Dactylogyrus spp. (Monogenean) in Nile tilapia (Oreochromis niloticus): hematology, immune response, histopathological investigation, and inflammatory cytokine genes of gills. BMC Vet Res 20: 334. [Google Scholar]
Ranasinghe S, Armson A, Lymbery AJ, Zahedi A, Ash A. 2023. Medicinal plants as a source of antiparasitics: an overview of experimental studies. Pathog Glob Health 117(6): 535–553. [Google Scholar]
Saengsitthisak B, Chaisri W, Mektrirat R, Yano T, Pikulkaew S. 2023. In vitro and in vivo action of turmeric oil (Curcuma longa L.) against Argulus spp. in goldfish (Carassius auratus). Open Vet J 13: 1645–1653. [Google Scholar]
Santos PR, Andrade-Porto SM, Brandão FR, Souza DCM, Rocha MJS, Sebastião FA, Oliveira MR, Chaves FCM, Chagas EC. 2023. Efficacy of the essential oils of Aloysia triphylla, Lippia gracilis and Piper aduncum in the control of Piscinoodinium pillulare (Shaperclaus, 1954) in Colossoma macropomum (Cuvier, 1818). Aquaculture 565: 739127. [Google Scholar]
Santos WB, Majolo C, Santos DS, Rosa MC, Monteiro PC, Rocha MJS, Oliveira MIB, Francisco Célio Maia Chaves FCM, Chagas EC. 2018. Eficácia in vitro de óleos essenciais de espécies de Piperaceae no controle do acantocéfalo Neoechinorhynchus buttnerae. Rev Bras Hig San Anim 12(4): 460–469. [Google Scholar]
Salgado-Moreno SM, Gutiérrez-Leyva R, Carmona-Gasca CA, Martínez-González S, Ramírez-Ramírez JC, De La Cruz-Moreno CO, Borrayo-González JJF. 2025. Garlic powder evaluation as feed additive on Nile tilapia (Oreochromis niloticus L.) growth performance, feed utilization, gill parasitic treatment, and monogenean diversity. Fishes 10: 34. [Google Scholar]
Sari EP, Budiyanto D, Wirawan I. 2024. Effect of papaya seed freshing (Carica papaya) with different dosage as an herbal medicine against the parasite Argulus indicus on gold cook fish (Carassius auratus). IJAM 4(2): 43–48. [Google Scholar]
Saengsitthisak B, Chaisri W, Yano T, Okonogi S, Pikulkae S. 2024. Antiparasitic efficacy and toxicity evaluation of Zingiber officinale Roscoe oil against Ichthyophthirius multifiliis in freshwater fish. J Vet Sci 14(2): 333–340. [Google Scholar]
Shah MD, Maran BAV, Haron FK, Ransangan J, Ching FF, Shaleh SRM, Shapawi R, Yong YS, Ohtsuka S. 2020. Antiparasitic potential of Nephrolepis biserrata methanol extract against the parasitic leech Zeylanicobdella arugamensis (Hirudinea) and LC-QTOF analysis. Sci Rep 10: 22091. [Google Scholar]
Shah MD, Tani K, Yong YS, Ching FF, Shaleh SRM, Vairappan CS, Balu Alagar Venmathi Mara BAV. 2021. Antiparasitic potential of chromatographic fractions of nephrolepis biserrata and liquid chromatography-quadrupole time-of-flight-mass spectrometry analysis. Molecules 26: 499. [Google Scholar]
Shaikh SA. 2025. Antiparasitic efficacy of Azadirachta indica seeds on the Argulus foliaceus fish parasite. IJAR 11(4): 323–325. [Google Scholar]
Sharma A, Kumar S, Raman RP, Kumar K, Kumari P, Brahmchari RK, Pawar NA, Dalvi RS, Jadhao SB. 2025. Biopesticidal efficacy and safety of azadirachtin: broad-spectrum effects on ectoparasites infesting goldfish, Carassius auratus (Linn. 1758). ACS Omega 10: 13269 − 13277. [Google Scholar]
Silva BAF, Falkenberg JM, Yamada FH. 2025. Diversity of parasites in two sympatric species of Brazilian tetras (Characiformes: Acestrorhamphidae) in the Caatinga Domain, Northeastern Brazil. Parasitologia 5: 8. [Google Scholar]
Silva JS, Brasil EM, Cipriano FDS, Magnotti C, Rocha VM, Furtado WE, Chagas EC, Chaves FCM, Owatari MS, Martins ML, Cerqueira VR. 2024. Antiparasitic efficacy of essential oils for Neobenedenia melleni infecting farmed Lebranche mullet (Mugil liza). Int Aquat Res 16: 187–194. [Google Scholar]
Soares BV, Cardoso ACF, Campos RR, Gonçalves BB, Santos GG, Chaves FCM, Chagas EC, Tavares-Dias M. 2017a. Antiparasitic, physiological and histological effects of the essential oil of Lippia origanoides (Verbenaceae) in native freshwater fish Colossoma macropomum. Aquaculture 469: 72–78. [Google Scholar]
Soares BV, Neves LR, Ferreira DO, Oliveira MSB, Chaves FCM, Chagas EC, Gonçalves RA, Tavares-Dias M. 2017b. Antiparasitic activity, histopathology and physiology of Colossoma macropomum (tambaqui) exposed to the essential oil of Lippia sidoides (Verbenaceae). Vet Parasitol 234: 49–56. [Google Scholar]
Steverding D, Morgan E, Tkaczynski P, Walder F, Tinsley R. 2005. Effect of Australian tea tree oil on Gyrodactylus spp. infection of the three-spined stickleback Gasterosteus aculeatus. Dis Aquat Org 66: 29–32. [Google Scholar]
Tang H, Guo S, Xue H, Guo Z, Li Y, Yu Q, Liu Y, Zhou W, Ye S. 2024. Antiparasitic efficacy of flavonoids identified from Psoralea corylifolia against Tetrahymena piriformis in guppy (Poecilia reticulate). Vet Parasitol 328: 110167. [Google Scholar]
Tavares-Dias M. 2018. Current knowledge on use of essential oils as alternative treatment against fish parasites. Aquat Living Resour 31: 13. [Google Scholar]
Tavares-Dias M, Ferreira GV, Videira MN. 2021a. Histopathological alterations caused by monogenean parasites the gills of tambaqui Colossoma macropomum (Serrasalmidae). Semina: Cienc Agrar 42: 2057–2064. [Google Scholar]
Tavares-Dias M, Neves LR, Alves CMG, Nogueira JN, Neves FB, Pinto AVP, Carvalho JCT, Ferreira IM. 2021b. In vitro anthelminthic activity of Lippia alba essential oil combined with silk fibroin against monogeneans of Colossoma macropomum (Serrasalmidae). Aquac Res 52: 5099–5104. [Google Scholar]
Tedesco P, Beraldo P, Massimo M, Fioravanti ML, Volpatti D, Dirks R, Galuppi R. 2020. Comparative therapeutic effects of natural compounds against Saprolegnia spp. (Oomycota) and Amyloodinium ocellatum (Dinophyceae). Front Vet Sci 7: Article 83. [Google Scholar]
Trasviña-Moreno AG, Ascencio F, Angulo C, Hutson KS, Avilés-Quevedo A, Inohuye-Rivera RB, Pérez-Urbiola JC. 2019. Plant extracts as a natural treatment against the fish ectoparasite Neobenedenia sp. (Monogenea: Capsalidae). J Helminthol 93: 57–65. [Google Scholar]
Tu X, Huang A, Hu Y, Ling F, Wang G. 2018. Arctigenin: An emerging candidate against infections of Gyrodactylus. Aquaculture 495: 983–991. [Google Scholar]
Tu X, Duan C, Wu S, Fu S, Ye J. 2021. Identification of plumbagin as an effective chemotherapeutic agent for treatment of Gyrodactylus infections. Aquaculture 535: 736372. [Google Scholar]
Tu X, Hu J, Peng J, Chen Q, Zhao Y, Gu Z. 2025. Discovery of thymoquinone analogues with high anthelmintic activity against monogenean infections in goldfish (Carassius auratus). Vet Parasitol 334: 110401. [Google Scholar]
Ukwa U, Saliu J, Akinsanya B, Asekun O. 2024. Efficacy of binary mixtures and antagonistic effect of Azadirachta indica on Afranamum melegueta against helminth parasites of fish in Epe lagoon. Sci Afr 23: e02072. [Google Scholar]
Valladão GM, Gallani SU, Pilarski F. 2015. Phytotherapy as an alternative for treating fish disease. J Vet Pharmacol Therap 38: 417–428. [Google Scholar]
Valentim DSS, Duarte JL, Oliveira AEMFM, Cruz RAS, Carvalho JCT, Conceição EC, Fernandes CP, Tavares-Dias M. 2018a. Nanoemulsion from essential oil of Pterodon emarginatus (Fabaceae) shows in vitro efficacy against monogeneans of Colossoma macropomum (Pisces: Serrasalmidae). J Fish Dis 41: 443–449. [Google Scholar]
Valentim DSS, Duarte JL, Oliveira AEMFM, Cruz RAS, Carvalho JCT, Solans C, Fernandes CP, Tavares-Dias M. 2018b. Effects of a nanoemulsion with Copaifera officinalis oleoresin against monogenean parasites of Colossoma macropomum: a Neotropical Serrasalmidae. J Fish Dis 41: 1041–1048. [Google Scholar]
Valerio CKU, Ferdosh S. 2025. A review of extraction techniques of bioactive compounds and pharmacological properties of Guam's invasive vine - Antigonon leptopus. Appl Sci 15: 5625. [Google Scholar]
Van PQ, Yilmaz BH, Yavuzcan H. 2021. In vitro antiparasitic activity of ginger (Zingiber officinale) bulb and pomegranate (Punica granatum) peel against monogenean fish parasite, Dactylogyrus sp. Acta Aquat Turc 17: 56–63. [Google Scholar]
Vercellini MC, García ID, Rearte R, Vargas S, Montes MM. 2024. Eugenol, menthol, and benzocaine as anesthetic and antiparasitic treatments for Cheirodon interruptus (Ostariophysi: Characidae). Aquacult Int 32: 3317–3329. [Google Scholar]
Vercellini MC, Carranza-Martín AC, Morote L, Maschi F, Montes MM. 2025. Eugenol-parasite interactions in ten spotted live-bearer fish Cnesterodon decemmaculatus: seasonal and host-related effects. Vet Parasitol Reg Stud Reports 62: 111288. [Google Scholar]
Wu Z, Ling F, Song C, Chen W, Wang G. 2017. Effects of oral administration of whole plants of Artemisia annua on Ichthyophthirius multifiliis and Aeromonas hydrophila after parasitism by I. multifiliis.. Parasitol Res 116: 91–97. [Google Scholar]
Yang Z, Tan X, Zhang Z, Han J, Qu S, Liu T, Wang G. 2022. Ononin: A candidate anti-parasitic drug isolated from Spatholobi caulis against infections of Dactylogyrus intermedius (Monogenea). Parasitol Int 88: 102535. [Google Scholar]
Yazdani AE, Mirzargar SS, Rahmati Holasoo H, Sharif zadeh A, Ebrahimzadeh MHA. 2021. In vitro study f short-term antiparasitic effect of alcoholic extract of Terminalia catappa L. leaves on Ichthyophthirius multifiliis theronts. Iranian J Fish Sci 20(4): 1138–1148. [Google Scholar]
Yildiz HY, Phan-Van Q, Parisi G, Sao MD. 2019. Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) juice against crustacean parasite, Lernantropus kroyeri, found on European sea bass (Dicentrarchus labrax). Ital J Anim Sci 18: 833–837. [Google Scholar]
Yildiz HY, Bekcan S. 2020. Control of ectoparasitosis in carp (Cyprinus carpio) induced by Gyrodactylus elegans (Monogenea) with garlic (Allium sativum) and onion (Allium cepa) extracts. Ecocycles 6(1): 10–17. [Google Scholar]
Yilmaz BH, Yildiz HY. 2023. Anthelmintic effects of peppermint (Mentha piperita), lemon (Citrus limon), and tea tree (Melaleuca alternifolia) essential oils against Monogenean parasite (Dactylogyrus sp.) on carp (Cyprinus carpio). Helminthologia 60(2): 125–133. [Google Scholar]
Yuan Y, Sun K, Li D, Hu J, Sun Y, Xie X, Zhang B, Zhou S, Yin F. 2025. Antiparasitic efficacy of aqueous green tea extracts and its key constituents against Cryptocaryon irritans in the Large Yellow Croaker (Larimichthys crocea). Aquaculture 607: 742627. [Google Scholar]
Zahra A, Bakkara OR, Miranti S, Irawan H, Wulandari R, Muzahar M, Yulianto T. 2023. Application of Rosmery (Rosmarinus officinalis) solution to reduce marine leeches in “cantang” hybrid grouper (Epinephelus fuscoguttatus x Epinephelus lanceolatus). BIO Web Conf 79: 13004. [Google Scholar]
Zhang Y, Tan X, Tu X, Ling F, Wang G. 2020. Efficacy and antiparasitic mechanism of curdione from Curcuma zedoaria against Gyrodactylus kobayashii in goldfish. Aquaculture 523: 735186. [Google Scholar]
Zhong ZH, Guo WL, Lei Y, Wang F, Wang SF, Sun Y, Hu WT, Zhou YC. 2019. Antiparasitic efficacy of honokiol against Cryptocaryon irritans in pompano, Trachinotus ovatus. Aquaculture 500: 398–406. [Google Scholar]
Zhou S, Li WX, Wang YQ, Zou H, Wu SG, Wang GT. 2017. Anthelmintic efficacies of three common disinfectants and extracts of four traditional Chinese medicinal plants against Gyrodactylus kobayashii (Monogenea) in goldfish (Carassius auratus). Aquaculture 466: 72–77. [Google Scholar]
Zhou S, Dong J, Liu Y, Yang Q, Xu N, Yang Y, Gu Z, Ai X. 2020. Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus). Aquaculture 521: 734992. [Google Scholar]
Zhou S, Dong J, Liu Y, Yang Q, Xu N, Yang Y, Ai X. 2021. Antiparasitic efficacy of herbal extracts and active compound against Gyrodactylus kobayashii in Carassius auratus. Front Vet Sci 8: 1–10. [Google Scholar]
Zhou S, Yang Q, Dong J, Liu Y, Xu N, Yang Y, Ai X. 2022. Anthelmintic efficacy of palmarosa oil and curcuma oil against the fish ectoparasite Gyrodactylus kobayashii (monogenean). Animals 12: 1685. [Google Scholar]
Zhu F. 2020. A review on the application of herbal medicines in the disease control of aquatic animals. Aquaculture 526: 735422. [Google Scholar]
Zoral MA, Futami K, Endo M, Maita M, Katagiri T. 2017. Anthelmintic activity of Rosmarinus officinalis against Dactylogyrus minutus (Monogenea) infections in Cyprinus carpio. Vet Parasitol 247: 1–6. [Google Scholar]
Zorin B, Gibson-Kueh S, Zilberg D. 2019. A novel treatment against the monogenean parasite, Gyrodactylus turnbulii, infecting guppies (Poecilia reticulata), using a plant-based commercial insecticide Timor C. Aquaculture 501: 313–318. [Google Scholar]

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